An FRT-flanked neo cassette was inserted upstream of exon 2 and loxP sites were inserted flanking exon 2 via homologous recombination. The neo cassette was removed by mating with mice expressing germline FlpE recombinase. (J:93799)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count