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TauLacZ was inserted into the locus along with a floxed neomycin resistance cassette. This caused the deletion of all of the coding sequence of the native gene. The neomycin resistance cassette was subsequently eliminated by Cre-mediated recombination. The ES line was generated in collaboration with Martyn Goulding, Salk Institute. Immunohistochemical analysis confirmed the absence of protein product. (J:123264)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
