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T126M, H122S, N124S and A125T mutations were introduced into exon 2 by homologous recombination. A Pol2neobpA cassette flanked by loxP sites was inserted into intron 2. Northern blot showed 3.5-fold marked-up regulation of the transcript in mutants. (J:94003)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
