A single loxP site was introduced in intron 7 and a floxed neomycin cassette was placed in intron 10. The neomycin cassette was later deleted by breeding to EIIa-cre mice leaving exons 8, 9, and 10 flanked by loxP sites. (J:94123)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count