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The human FGF19 cDNA was ligated to a rat myosin light chain 2 promoter and followed by the splice donor/acceptor sites present between exons 4 and 5 of the human growth hormaone gene. RT-PCR analysis of skeletal muscle biopsies showed the presence of human transcript in transgenic mice. Transgenic protein was verified by enzyme-linked immunosorbent assay. This record is a representative transgene as founder lines were not named. (J:76323)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
