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A modified human albumin promoter with a tet responsive element drives expression of cre recombinase. In the same vector, expression of the tetracycline silencer, rtTA, is driven by the CMV promoter. In the absence of tetracycline, cre expression is repressed. In the presence of tetracycline cre expression is seen in the liver. Four founders were generated. (J:93624)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
