Log In|Sign Up
EN
ES cells with the Lattm2.1Mal allele were additionally targeted to mutate tyrosine codon 136 to phenylalanine (p.Y136F). Western blot shows that the amount of protein in mutant thymocytes is similar to that of wild-type. A floxed neo was inserted between exons 9 and 10 and subsequently removed by crossing with deleter mice. (J:94074)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
