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In this transgene construct, the cDNA encoding the human APP mutant bearing the Swedish (KM595/596NL) and London (V6421) mutations is under the control of the murine Thy1 promoter. Lines 26 and 28 expressed high levels of transgene. Line 28 was described. (J:86694)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
