The E1-T127 transgene was designed with a 4.3 kb rat elastase 1 (Ela1 or E1) gene upstream control region, the simian virus 40 large T- and small t-antigen (TAg) coding sequence containing amino acids 1-127 followed by 4 amino acids (Asn, Gln, Asn, and Cys) from the shifted reading frame and a polyA signal. (J:78026)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count