This allele, associated with natural resistance to infection by ecotropic Friend murine leukemia virus (FLV, MuLV) and Murine sarcoma virus, was identified in several wild mouse populations in Japan, Southeast Asia and western North America. Sequencing demonstrated that the allele contains ecotropic MuLV-related proviral sequence beginning in the C-terminal end of the pol region and extending through the env region and the 3' long terminal repeat. (J:7952)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
multiple strains
Spontaneous
Viral insertion
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9

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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