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The transgene contains ~700-bp of the rat insulin promoter (RIP-1) and a 1.8-kb mouse Neurod1 coding region with its amino terminus fused to a Myc tag. The rat insulin promoter is used to drive the transgene expression in pancreatic islets. Transgene expression, as shown by immunostaining using anti-Myc tag antibody, is detected in the pancreatic islets but not in the brains of P30 rescued mice. (J:74715)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
