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The transgene contains a 2.1kb sequence of human keratin 14 promoter upstream of the mouse baculoviral IAP repeat-containing 5 (Birc5) gene and a 2.2kb sequence of the human growth hormone and polyadenylation sequence. Transgene expression is specific to epidermal and follicular keratinocytes. Five founder mice were established and line 19 was chosen as the representative line.
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
