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Pigeon cytochrome c was engineered for expression in lymphoid tissues of transgenic mice in two forms. The cytochrome C in this construct is targeted to the mitochondria after cytoplasmic synthesis (ePCC). mRNA expression levels are lower in mice carrying this transgene than in mice carrying Tg(H2KmPCC)2939. PCC was expressed in thymus, spleen and LPS stimulated B cells as determined by Northern blot. (J:92997)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
