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The transgene contains the murine albumin promoter and enhancer sequences, and the entire human lecithin-cholesterol acyltransferase (LCAT) gene with 550 bp of 3' untranslated region. Plasma LCAT activities in transgenic mice are increased by 2.6- to 10.8-fold over the non-transgenic controls. (J:93245)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
