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Crossing Fosl1tm2Wag with mice expressing Cre in the embryo proper created this allele in which the floxed region containing exons 3 and 4 (containing the dimerization and the DNA-binding domains) was excised. Upon excision, the 3' GFP was spliced to the N-terminal part of the transcript and was thereby activated. Western blot detected the fusion protein using an anti-GFP antibody. Immunofluorescence confirmed GFP activation. (J:93053)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
