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This line carries ten copies of the human poliovirus receptor transgene (PVR). The human polio virus receptor is a member of the Igg superfamily. Northern and Western blot analyses detected expression of the transgene at levels three times higher in mice carrying this transgene, compared to levels in transgenic mice carrying a single copy of human PVR. (J:92990)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
