Exons 3 and 4 were deleted following Cre-mediated excision of a floxed neo. A 3' mRNA splice junction of exon 3 was retained. Immunoblot and flow cytometry confirmed protein expression by B cells. Protein migrated as a 120 kDa fragment, the predicted size of the protein lacking two immunoglobulin-like domains. (J:92736)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count