The transgene contains a bacterial lacZ gene linked to a 2.2 kilobase 5'-flanking sequence derived from the human glial fibrillary acidic protein gene. The human GFAP promoter sequence has been shown to direct astrocyte-specific transcription in cultured cells. (J:92866)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count