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LoxP sites were inserted to flank exon 1. In addition, EGFP-FRT-flanked neomycin cassette was inserted 3' to exon 1. The floxed exon was removed by mating mutant animals to the cre deleter strain FVB/N-Tg(EIIa-cre)C5379Lmgd/J. Protein was undetectable by Western blot analysis of bladder proteins. The EGFP-neomycin cassette was not removed by Cre recombinase. (J:92539)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
