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The transgene contains the mouse whey acidic protein promoter and a rat preproIgf1 cDNA (insulin-like growth factor 1), which lacks 186 bp sequence of exon 1 and exon 5. The cDNA encodes 38 bp of 5'UTR, 48 amino acids of the signal peptide, the 70 amino acid mature peptide, the 35 amino acid Ea trailer peptide, and 13 bp of 3'UTR. (J:92578)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
