A gene trap vector containing pKOS-lacZ/MC1neo (Lexicon Genetics, Woodlands, TX) was inserted to replace the first four exons of the gene. Western blot analysis on platelets, lung, muscle and adipocytes did not detect protein. (J:92404)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count