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An eGFP and floxed neo were inserted in frame into exon 1, deleting most of exon 1 and all of exon 2, thereby removing about 80% of the open reading frame, including the homeodomain. The floxed neo was excised by crossing mice with mice expressing cre in the germ line. PCR confirmed recombination in mutant mice. (J:91405)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
