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A transgene insertion resulted in a translocation between chromosomes 7F and 14C and a deletion on chromosome 7C of at least 1 Mb. This deletion contains at least 6 genes including; Cttn, Fadd, Fgf3, Fgf4, Fgf15, and Ccnd1. The transgene contained a chicken Actb promoter, CMV-IE enhancer and a full length human PEG8 cDNA. Expression of the transgene is not thought to be involved in this phenotype. (J:89381)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
