Exon 8 was disrupted by the insertion of a neomycin resistance gene in the opposite transcriptional orientation to the endogenous gene. Southern blot confirmed recombination in ES cells. (J:40673)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count