A targeting vector was constructed to replace promoter and the transcription start site, but not the translation start codon, with the SV40 minimal promoter plus five copies of the Gal4 DNA sequences. Flow cytometry showed mutant mice had very few T cells expressing the antibody. (J:92288)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S4/SvJae
Targeted
Insertion, Intragenic deletion
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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