An IRES-cre-FRT-pgk-hygro-FRT cassette was inserted into exon 2. Crossing with Flp expressing mice excised the pgk-hygro sequences. PCR confirmed recombination in mice. Cre expression mirrored expression of the endogenous gene. (J:92294)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count