A floxed neo cassette and a LoxP site were inserted flanking exon 2, which encodes slightly more than five of the seven transmembrane-spanning domains. RT-PCR revealed decreased mRNA expression from the mutant allele. (J:92301)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count