A floxed Betageo cassette was inserted into intron 2. PCR confirmed recombination in mice. Northern blot demonstrated that transcription was abolished and Western blot indicated a complete absence of protein in mutant brains. (J:92302)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count