Log In|Sign Up
EN
The transgene contains mouse apolipoprotein A-II sequence from Swiss 3T3 cells with 4.5 kb of upstream sequence and 8.5 kb of downstream sequence. About 10 copies of the transgene integrated into the genome. The apoA-II expressed from the Swiss 3T3 cell genomic clone carries a more basic apoA-II allele (found among many inbred strains of mice) than the C57BL/6J apoA-II allele. Expression of the transgene in the liver was 4-fold higher than endogenous gene expression. (J:92454)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
