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This transgene consists of a minimal promoter, 1.8 kb of murine Pax6 intron 4 encoding a retinal specific regulatory element, a cre recombinase gene, an IRES, a GFP gene, and a polyadenylation signal. Cre and GFP expression are seen in retinal progenitor cells. Line two contains 4 copies of the trandgene inserted into Chr 7 (Chr7: 8525949685287099) to produce a 27 kb deletion. (J:68851, J:325619)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
