This transgene consists of a 1.58kb fragment of the myogenin promoter, an 800 bp cDNA of the murine Ntf3 gene, and 2.1 kb of the human HGH gene including exons, introns, and a polyadenylation signal. Increased Ntf3 expression is seen the muscles from E11.5 to 5 weeks after birth. Three lines were generated (5150, 5158, 5160), only 5160 was selected for further study. (J:43444)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x CBA)F1
--
Insertion
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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