A loxP site was inserted upstream of exon 9 and a FRT-flanked PGK-neo downstream, with a loxP site at the most 3'end. Crossing with Cre-deleter mice excised the floxed sequence, removing exon 9 and the neo. Exon 9 contains predicted active sites for an acyltransferase. (J:89228)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Disruption caused by insertion of vector
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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