A loxP site was inserted upstream of exon 2, which contains the ATG, and an FRT flanked PGK-neo with a loxP site and lacZ downstream. Crossing with Cre deleter mice creates this allele in which exon 2 and the neo are excised, leaving a lacZ and single loxP. (J:89228)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count