A 1.7 kb direct tandem repeat unit in the DMR (the K repeat) was replaced with a floxed neomycin resistance gene cassette, which was subsequently excised via transiently expressed Cre-mediated recombination. Northern blot showed no significant difference in gene expression between mutant and wild-type tissues. (J:91593)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion, Intragenic deletion
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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