Log In|Sign Up
EN
This transgene contains the MMTV (mouse mammary tumor virus) promoter and a 4.6 kb cDNA from the rat Erbb2 (avian erythroblastosis B2) oncogene. The activated form of the gene is used in this construct, which differs from the wild-type allele by a point mutation, Val664Glu. Six transgenic lines were produced (NA, NB, NF, NK, NL and NM). (J:48632)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
