2.3 kb encompassing most of a differentially methylated region spanning 1A, 612 bp upstream of the promoter, was replaced with a floxed cassette containing Tkneo-pA, URA3 and tACE-Cre-pA. The cassette was deleted upon germ-line transmission, leaving a single loxP site. (J:91717)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count