A retroviral vector containing a selection marker, termination codons in all reading frames, a splice acceptor and a transcription terminator was inserted into the locus. PCR and RT-PCR confirmed recombination as well as inactivation of the gene. (J:91683)
Basic Information
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count