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This transgene expresses cre recombinase under the control of the mouse type II collagen gene promoter. Analysis of the insertion site indicated that 7 copies of the transgene were present. Cre activity was detected in the otic vesicle and notochord at E9.5 and in somites, otic vesicle, branchial arches and the hindbrain at E10.5. At E12.5-15.5, activity was detectable in cartilagenous skeletal elements. (J:82028)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
