Crossing Pax8tm1(cre)Mbu with mice expressing FLP recombinase in the germline created this allele in which the frt-flanked neo downstream of the inserted Cre was excised, allowing Cre to be expressed. Expression of cre recombinase was detected in the known Pax8 expression domains; in addition, expression was detected in the adrenal gland, and in the facial, vestibulocochlear and cuneate nerves. (J:89762)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count