Human PDGFB, as well as an IRES-lacZ gene and floxed neo replaced some 5' sequence of the coding region. Southern blot and PCR confirmed incorporation of PDGFB. In situ hybridization using human PDGFB also confirmed expression of the knock in gene. (J:90898)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Insertion
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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