Human PDGFB, as well as an IRES-lacZ gene and floxed neo replaced some 5' sequence of the coding region. Southern blot and PCR confirmed incorporation of PDGFB. In situ hybridization using human PDGFB also confirmed expression of the knock in gene. (J:90898)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count