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A gene trap vector pPAT containing intron 1 and the splicing acceptor from Fyn, lacZ-pA, Ampr, PGK-neo and the splicing donor from Fyn was inserted at the 3' end of the endogenous gene. Northern blot of mutant mice indicated no wild-type transcripts present in brain, testis or kidney, but showed evidence of fusion transcripts between the neo and the 3' end of Rab3ip. RT-PCR of mutant kidney and testis confirmed lack of wild-type transcript. (J:29606)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
