Wnt1 was knocked-in to the endogenous En1 locus. Exon 1 was replaced with Wnt1 and an IRES-lacZ and floxed neo. In situ hybridization indicates Wnt1 expression was expanded according to the En1 expression pattern. (J:91004)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count