Log In|Sign Up
EN
This allele was generated from Fmn1tm1Zlr by crossing to Tg(CMV-cre)1Cgn mice. Cre expression causes the excision of 170 kb containing the remaining exons between 9 and 24; the hygro cassette is also deleted. The predicted protein product is similar to that of Fmn1tm1Zlr in that the translation is out-of-frame after exon 9. In addition, transcription of Grem1 is disrupted owing to the deletion of a Grem1 regulatory region in an Fmn1 intron. (J:91385)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
