The entire coding region immediately following the start codon was removed and replaced with an IRES-Cre and FRT-flanked neo cassette. Southern blot confirmed recombination. Immunohistochemistry confirmed expression of Cre. (J:90717)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count