A cassette containing an IRES-Cre and FRT-flanked neo was inserted 50 bp upstream of the stop codon. Southern blot confirmed recombination. Immunohistochemistry indicated that cells expressing the endogenous gene also expressed Cre. (J:90717)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count