LoxP sites were inserted around exon 2 and after a PGK-neo cassette in intron 2 via homologous recombination. Western blot analysis confirmed protein expression from the mutant allele (J:91025)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count