This mutation was caused by the insertion of the gene trap vector pGT0TMp into the 3rd intron. The fusion protein includes the first endogenous 121 amino acids, containing the signal sequence and about half of its globular domain VI, followed by the transmembrane domain and Betageo reporter from the vector. (J:67920, J:85792)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
1
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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