This mutation was caused by the insertion of the gene trap vector pGT0TMp into the 3rd intron. The fusion protein includes the first endogenous 121 amino acids, containing the signal sequence and about half of its globular domain VI, followed by the transmembrane domain and Betageo reporter from the vector. (J:67920, J:85792)
Basic Information
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count