A neomycin gene was inserted into an exon encoding part of the Dbl homology domain. Southern blot confirmed recombination and Western blot from adult brain indicated that wild-type protein could not be detected in mutants. (J:91065)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count