Loxp sites were inserted to flank exon 3, which encodes the DNA binding domain. An FRT-flanked neo was removed via transient FLP-mediated excision. Recombination was confirmed by Southern blot and PCR. (J:89880)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count