Loxp sites were inserted to flank exon 3, which encodes the DNA binding domain. An FRT flanked neo was inserted in inton 2. Recombination was confirmed by Southern blot and PCR. (J:89880)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count